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Officials said it was not clear whether the explosion was caused by a suicide car bombing or a vehicle rigged with explosives and detonated by remote control.
At least seven people, including a child, were injured in the attack, Ahram Online reported, quoting Egypt’s Ambulance Authority.
The explosion took place near Ibrahim’s residence in the capital’s Nasr City district, according to state-run MENA news agency.
Criminal investigators and explosion experts were immediately sent to the scene.
The Interior Minister is in charge of Egypt’s police force.
Nasr City was the site of one of the protest camps.