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There have been some in the senior ANC cadre calling for Zuma to step down following allegations of corruption.
The warning comes after dozens in neighboring Zimbabwe appear to have contracted the disease.
The rand weakened against the dollar since mid-December, while international oil prices continued to crawl upward.
Zuma's critics allege he is trying to protect those with whom he has strong business ties.
South Africa's set of trials for a new vaccine are the first such wide-scale effort in a decade.
Castro led Cuba for decades before handing power to his brother in 2008.
Zuma's office has told a former public protector behind the State Capture report to stop making comments about it.
A revitalized economy is now pushed back to begin in Q2 2017, rather than the beginning of the new year.
The report does not provide proof of criminal wrongdoing by President Jacob Zuma.
South Africa's National Prosecuting Authority reviewed the fraud charges and found them without merit.